教师简介
姓名：杨帆 性别：男
出生年月：1989.03 籍贯：山东德州
职称：副教授 职务：院长助理
毕业院校：南京大学 理学博士
电子邮箱：yangf@dzu.edu.cn
联系电话：17615930302
通信地址：山东省德州市德城区德州学院
政治面貌：中共党员
硕士生导师：德州学院硕士研究生导师，新疆大学、山东理工大学、吉林化工学院兼职硕士生导师
研究方向：
1. 新型荧光探针创制及重大疾病早期诊断；
2. 智能可穿戴纺织品。
教育工作经历：
本科，2007.09-2011.06，山东师范大学，化学工程与工艺
硕士，2011.09-2014.06，山东师范大学，分析化学
博士，2014.09-2018.12，南京大学，化学
2019.06-2021.12，德州学院纺织服装学院，讲师
2022.01-至今，德州学院纺织服装学院，副教授
2024.07-2024.10，芬兰坦佩雷应用科学大学，访问学者
科研项目：
1．国家自然科学基金青年项目：22104010，基于实时监测内源性次氯酸的骨关节炎早期诊断新方法研究，2022.01-2024.12，30万元，已结题，主持；
2．山东省自然科学基金青年项目：ZR2021QB141，用于骨关节炎早期诊断的新型荧光寿命探针的设计与合成，2022.01-2024.12，15万元，已结题，主持；
3．山东省高等学校青年创新团队计划项目——“先进荧光材料与早期诊断创新团队”：2023KJ271，高灵敏荧光探针创制及骨关节炎早期诊断研究，2024.01-2026.12，在研，主持；
4. 南京大学生命分析化学全国重点实验室开放研究项目：SKLACLS2016，2020.04-2023.03，5万，已结题，主持；
5. 山东师范大学分子与纳米探针教育部重点实验室开放课题研究项目：2020KLMNP04，2021.01-2022.12，3万，已结题，主持；
6. 青岛科技大学山东省生化分析重点实验室开放课题项目：SKLBA2308，2023.08-2025.08，2万，已结题，主持；
7. 校企联合攻关项目：新型次氯酸荧光试剂盒的研发，2022.06-2024.12，50万，已结题，主持。
8. 校企联合攻关项目：智能纺织品及功能性纱线开发，2025.11-2026.12，50万，在研，主持。
9. 德州市重点研发计划（政策引导类项目）：ZD2025ZC026，用于无创实时监测伤口炎症的智能手机辅助双模式碳量子点敷料，2026.01-2027.12，主持。
发明专利：
1．杨帆，孙婉，张梅，马洪才，张赛，王伟，宋新蕾，董毅卿，李嘉茗，一种比率荧光探针及其制备方法和应用：202410069665.1
2．杨帆，项龙飞，张梅，张赛，宋新蕾，时佳梦，王赠凯，袁中轩，一种荧光探针及其制备方法与应用：202311054391.0
3．孙婉，杨帆，程振原，董荣千，王程，周厚泽，一种pH荧光探针及其制备方法和应用：202410902657.0
4．张伟，曲铭海，杨帆，一种纺织品除皱机构：202110548908.6
5．张赛，韩华，吕志军，张梅，马洪才，曲铭海，杨帆，王伟，一种生姜粉复合粘胶纤维、制备方法及其应用：202410814222.0
6．王鲁敏，赵泽雨，冯传起，李欣，钱兆红，贾春晓，牛萍，杨帆，孟祥华，张雨婷，一种同时检测多元前列腺癌标志物的纸芯片及其制备方法和应用： 202510352241.0
7. 杨帆，徐静，卞志勇，徐培明，陈玉婷，徐冬梅，Imine Molecular Sensor with Two-Conversion and Three-Response to Acid-Alkaline Changes and Application Thereof: LU505207. 卢森堡专利2025.01.13
8. 孙婉，王雪峰，程振原，杨帆，吴娟娟，董荣千，陈昊，罗顺驰，张梓康，低浓度比率型高浓度增强型荧光探针及其制备方法和应用：202510820178.9
软件著作权：
1. 德州学院，杨帆，王一洲，荧光探针定量分析及可视化结果输出软件V1.0：2026SR0224937
2. 德州学院，杨帆，王一洲，金属离子溶液荧光图像浓度解析系统V1.0：2026SR0224590
成果转化：
一种比率荧光探针及其制备方法和应用，南京南达光光电科技有限公司，8万，2024.12
企业标准：
1. 杨帆，黄雍宝，刘凤艳，张梅，张帅，纺织品面料重金属铜离子检测标准，2025.06
2. 张梅，张赛，杨帆，李德志，刘明哲，薛小彬，粘胶涤纶混纺喷气涡流纺纱，2020.03
平台：
功能高效生态染整技术及应用德州市工程中心主任。
团队：
山东省高等学校“青创团队计划”团队，2023KJ271，2024.01-2026.12，先进荧光材料与早期诊断创新团队，高灵敏荧光探针创制及骨关节炎早期诊断研究，杨帆，孙婉，王伟，白茹冰，宋焱，张帅，吴娟娟。
期刊文章：
1. Zhengjia Wang, Yongbao Huang, Menghan Kang, |Hao Hou, Ruofei Zhu, |Sai Zhang, Shuai Zhang, Minghai Qu, Fan Yang, Construction and research progress of fluorescent carbon dots in intelligent anti-counterfeiting ink system. Coloration Technology, 2026, 1–46.
2. Wan Sun, Xuefeng Wang, Fan Yang, Mingqiong Tong, Rongqian Dong, Chunbo He, Jin-E. Wang, Chao Zhu, Yue-Wu Zhao, Zhonglin Lu, Fluorescence and photothermal dual-modal image guided integrated diagnosis and treatment. Colloids and Surfaces B: Biointerfaces, 2025, 254, 114828.
3. Rongqian Dong, Zhenyuan Cheng, Hao Chen, Zikang Zhang, Shunchi Luo, Yi Hou, Juanjuan Wu, Ning Zhang, Yongbao Huang, Chunyan Sun, Yaqing Ge, Fan Yang, Wan Sun, Low-concentration ratiometric and high-concentration enhancing fluorescent probe for HClO visualization detection. Dyes and Pigments, 2025, 243, 113013.
4. Xiaolei Zhang, Dongjun Lv, Zhongmin Liu, Dongmei Xu, Fan Yang, Qi Tang, Lifeng Zhong, Zhihua Liang, Qianchi Jia. From waste to resource: engineering biochar through optimized HCl activation for microplastic mitigation. Chemical Engineering Science, 2025, 304: 121091.
5. Shuai Zhang, Jiantao Zhu, Yan Song, Mei Zhang, Minghai Qu, Fan Yang, Rubing Bai, Huanjie Chi, Jinkun Wang, Junzhi Ma. Sodium alginate and hydroxypropyl methylcellulose hierarchical control of surface tension on silk fabrics for clean and efficient inkjet printing. International Journal of Biological Macromolecules, 2025: 140981.
6. Fengfeng Feng, Dongcheng Xiao, Fan Yang, Hao Liu, Minghai Qu, Weijie Wang. Self-assembled Nanostructures of Noncovalent Giant Amphiphilic Molecules Composed of Hydrophobic Isobutyl BPOSS and Hydrophilic POM in Different Cosolvents. Langmuir, 2025, 41(8): 5371-5378.
7. Li Zong, Zhen Li, Fan Yang, Tao Xu, Caiyun Zhang, Tengfei Xu. Enhanced performance of Co-doped antimony electrode for pH measurement in marine environments. Journal of Analysis and Testing, 2024, 9, 32-49.
8. 张赛, 董硕, 董东东, 葛效成, 陈振远, 王蕊鑫, 孙召彬, 杨帆. 单向导湿抗菌敷料的制备及性能研究. 棉纺织技术, 2024, 52(09): 34-40.
9. Qiuyu Wang, Sai Zhang, Jiayi Jiang, Shaojuan Chen, Seeram Ramakrishna, Wenwen Zhao, Fan Yang, Shaohua Wu. Electrospun radially oriented berberine-PHBV nanofiber dressing patches for accelerating diabetic wound healing. Regenerative Biomaterials, 2024, 11: rbae063.
10. Hang Yue, Chao Lu, Chunhong Wang, Fan Yang. Optimizing tensile strength and failure prediction in hemp fiber composites: Coupling effects of microfibril angle and fiber orientation under off-axis loading. Industrial Crops and Products, 2024, 222: 119872.
11. Fan Yang, Xinlei Song, Mei Zhang, Hongcai Ma, Sai Zhang, Wei Wang, Rui Wang, Zengkai Wang, Zhongxuan Yuan, Dongyin Ren, Wan Sun. Mitochondria-targeting phenothiazine-based ratiometric fluorescent probe for visual and rapid detection of hypochlorous acid in living cells and zebrafish. Dyes and Pigments, 2024, 229: 112258.
12. Yan Wang, Senli Wang, Zhenyuan Cheng, Rongqian Dong, Xiangdi Jia, Fan Yang, Wan Sun. Temperature sensitive PNIPAm-g-PEI/gold nanotriangle for gene delivery promotion. Molecular Biotechnology, 2024: 1-9.
13. Yan Song, Kai Nie, Huan Liu, Wei Jiang, Yuanming Zhang, Rubing Bai, Fan Yang, Arthur Ragauskas, Junzhi Ma. Separation Process of Plant Fibers for Textile and Composite Application: A Review of Recent Advances. Journal of Natural Fibers, 2024, 21(1): 2406460.
14. Zhixin Shang, Dongyin Ren, Fan Yang, Jin Wang, Bing Liu, Feiyong Chen, Yufeng Du. Simultaneous immobilization of V and Cr availability, speciation in contaminated soil and accumulation in ryegrass by using Fe-modified pyrolysis char. Journal of Hazardous Materials, 2024, 469: 134097.
15. Xiaolei Zhang, Dongjun Lv, Zhongmin Liu, Dongmei Xu, Fan Yang, Xiaoli Wang, Zong Tan, Wei Gao, Ruoxuan Liu, Chunyu Su. Removal of polystyrene microplastic from aqueous solutions with London Plane bark biochar: Pyrolysis temperature, performance and mechanism, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 694, 134159.
16. Chuanwen Niu, Yuanying Shen, Mei Zhang, Fan Yang, Rubing Bai, Sai Zhang, Wei Wang, Yuxia Jin, Yanjun Xing, Wei Xiong, Hongwei Liu. Preparation of Zn-based MOFs photoluminescent coatings on cotton fabrics and their application in anti-counterfeiting. Surfaces and Interfaces, 2024, 53: 105054.
17. Yongbao Huang, Zhengjia Wang, Fengfeng Feng, Yan Wang, Ruofei Zhu, Xiaolei Zhang, Sai Zhang, Minghai Qu, Fan Yang. Ratiometric Fluorescent Probes for Copper Ion Detection and Cuproptosis Studies. Current Analytical Chemistry, 2024.
18. Fengfeng Feng, Sai Zhang, Weijie Wang, Chengyang Hong, Mei Zhang, Fan Yang, Yuxin Peng, Fucheng Jia, Hao Liu. Two-dimensional crystallization of precise side-chain giant molecules with constant building blocks ratio. Giant, 2024, 19: 100304.
19. Luzhi Yan, Xiaolei Zhang, Dongjun Lv, Zhongmin Liu, Fan Yang, Yijun Gao, Xiaoli Wang, Yaolian Jiang, Bing Zhao. Sensing of the charge transfer process in ZnO/MAPbI3 heterojunctions of perovskite solar cells (PSCs) by surface-enhanced Raman scattering. Journal of Materials Chemistry C, 2023, 11: 9179-9188.
20. Kai Zhang, Yue Huang, Yu Gu, Fan Yang. Nan Hao, A novel isothermal amplification strategy for rapid and sensitive detection of matrix metalloproteinase 2 using a bipedal DNA walker in anti-aging research. Sensors and Actuators B: Chemical, 2023, 397: 134650.
21. Xuefeng Wang, Xinlei Song, Juanjuan Wu, Pingxuan Dong, Xiaoxia Men, Xiaolei Zhang, Fan Yang, Wan Sun. Mitochondria-targeting two-photon fluorescent probe for sequential recognition of Cu2+ and ATP in neurons and zebrafish. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 303: 123260.
22. Xuefeng Wang, Zhenyuan Cheng, Juanjuan Wu, Fan Yang, Zhaozhi Zhang, Fang Tang, Wan Sun, Aixiang Ding. Rapid and sensitive detection of endogenous HClO in living cells and zebrafish using a phenothiazine-based fluorescent probe. Tetrahedron, 2023, 145: 133605.
23. Dongyin Ren, Mei Zhang, Guangshuo Han, Zhanzhao Li, Lan Yang, Xiaolong Li, Yuhua Gong, Zhixin Shang, Fan Yang. Preparation of CO2/N2-switchable hydrogel beads and adsorption, desorption, regeneration for Cu(II). Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 674: 131882.
24. 李冠志, 庄维达, 张赛, 杨帆, 汪军. 空气过滤用抗菌非织造材料的研究与应用.合成纤维, 2023, 52(09):38-43.
25. Sai Zhang, Mei Zhang, Rubing Bai, Lingqian Kong, Hongfang Yang, Anhui Zhang, Shuo Dong, Mengyi Chen, Seeram Ramakrishna, Fan Yang. Electrospun coaxial nanofibers loading with perovskite and icariin to enhance the bone scaffold-mediated osteogenesis. Materials Today Chemistry, 2022, 26: 101246.
26. Fan Yang, Wei Wang, Mei Zhang, Wenxin Tao, Youwang Wang, Jiameng Shi, Yuedi Ding, Minhao Xie, Sai Zhang, Zhenqiang Fan, Kai Zhang. CRISPR/Cas12a-mediated electrochemiluminescence platform for environmental and human serum SARS-CoV-2 RNA monitoring using a self-enhanced ruthenium complex linked to zeolitic imidazole framework-8. Environmental Science: Nano, 2022, 9(9): 3417-3426.
27. Wan Sun, Xiangling Gu, Pingxuan Dong, Lianjun Chu, Zhongyu Zhang, Zhenyuan Cheng, Fan Yang. Cell-membrane-targeted near-infrared fluorescent probe for detecting extracellular ATP. Analyst, 2022, 147(18): 4167-4173.
28. Xiaohong Wang, Fan Yang, Jianbin Pan, Bin Kang, Jingjuan Xu, Hongyuan Chen. Quantitative imaging of pN intercellular force and energetic costs during collective cell migration in epithelial wound healing. Analytical Chemistry, 2020, 92(24): 16180-16187.
29. Jianhua Wang, Zhaoshuai Gao, Pei Song, Pavel N. Melentiev, Xiaohong Wang, He Gao, Fan Yang, Bin Kang, Jingjuan Xu, Hongyuan Chen. How gain layer design determines performance of nanoparticle-based spaser. The Journal of Physical Chemistry C, 2020, 124(30): 16553-16560.
30. Fan Yang, He Gao, Shanshan Li, Rui-Bing An, Xiaoyang Sun, Bin Kang, Jingjuan Xu, Hongyuan Chen. A fluorescent τ-probe: quantitative imaging of ultra-trace endogenous hydrogen polysulfide in cells and in vivo. Chemical Science, 2018, 9(25): 5556-5563.
31. Pei Song, Jianhua Wang, Miao Zhang, Fan Yang, Haijie Lu, Bin Kang, Jingjuan Xu, Hongyuan Chen. Three-level spaser for next-generation luminescent nanoprobe. Science Advances, 2018, 4:eaat0292.
32. ShanShan Li, Qingying Kong, Miao Zhang, Fan Yang, Bin Kang, Jingjuan Xu, Hongyuan Chen. Plasmon-resonance-energy-transfer-based spectroscopy on single nanoparticles: biomolecular recognition and enzyme kinetics. Analytical Chemistry, 2018, 90(6): 3833-3841.
33. Qingying Kong, Fan Yang, Juan Song, Yifan Ruan, Shanshan Li, Zhaoshuai Gao, Bin Kang, Honyuan Chen, Jingjuan Xu. Revealing transient events of molecular recognition via super-localization imaging of single-particle motion. Scientific Reports, 2019, 9(1): 4870.
34. Tingting Zhang, Fan Yang, Xiangling Li, Wei Zhao, Jingjuan Xu, Hongyuan Chen. A multifunctional silver nanocomposite for the apoptosis of cancer cells and intracellular imaging. Chemical Communications, 2017, 53(41): 5614-5617.
35. Fan Yang, Tingting Zhang, Shanshan Li, Pei Song, Kai Zhang, Qiyuan Guan, Bin Kang, Jingjuan Xu, Hongyuan Chen. Endogenous microRNA-triggered and real-time monitored drug release via cascaded energy transfer payloads. Analytical Chemistry, 2017, 89(19): 10239-10247.
36. Wen Zhang, Ping Li, Fan Yang, Xiufen Hu, Chuanzhi Sun, Wei Zhang, Dezhan Chen, Bo Tang. Dynamic and reversible fluorescence imaging of superoxide anion fluctuations in live cells and in vivo. Journal of the American Chemical Society, 2013, 135(40): 14956-14959.
获奖：
1. 杨帆，王伟，曲铭海，张赛，孙婉，黄雍宝，张梅，冯逢逢，任冬寅，高灵敏荧光探针创制及骨关节炎早期诊断研究，2024年度山东化学化工学会自然科学奖二等奖；
2. 杨帆，张梅，曲铭海，王荣燕，崔万玲，张赛，孙婉，王伟，王金坤，黄雍宝，新型伤口炎症诊疗一体化管理的智能敷料高效制备及作用机制研究，2025年第八届山东省科技工作者创新大赛入围奖；
3. 杨帆，张梅，任冬寅，张赛，白茹冰，基于碳量子点层层组装抗菌及防紫外线织物的制备，2024年度德州学院实验技术成果奖二等奖；
4. 张梅，白茹冰，杨帆，张帅，申元颖，崔健，牛传文，曲铭海，张庆法，王金坤，蚕丝羊绒色纺高蓬松毛绒纱生产关键技术及产业化，2025年度中国纺织工业联合会科技进步奖二等奖；
5. 张梅，张赛，徐静，杨帆，冯逢逢，白茹冰，张会青，姜晓巍，朱莉娜，基于产业转型升级背景下的《纺纱学》课程体系构建与实践，2023年度中国纺织工业联合会纺织高等教育教学成果奖特等奖；
6 徐静，赵萌，郭琪，曲铭海，杨帆，王秀芝，王秀燕，伊芹芹，李学伟，张梅，姜晓巍，杨镇，许长海，姜兆辉，李金泉，“筑特融新数智引领多元赋能”新工科育人模式创新与实践，2025年度德州学院校级教学成果奖特等奖；
7. 郭琪，王秀芝，赵萌，曲铭海，杨帆，王伟，戴宏钦，王蕾，伊芹芹，赵伟，“能力进阶虚实互补产教协同”三位一体服装人体工学教学创新与实践，2025年度校级教学成果奖特等奖。
学术交流：
1. 20251219-20251221，北京，在第三届先进材料与智能传感器件研讨会先进纳米材料与智能传感器件论坛作报告，题为“新型碳量子点荧光探针创制及实时监测伤口炎症智能敷料”，获最佳墙报奖。
2. 20251226-20251228，徐州，在第二届化学与生物成像材料与技术创新发展大会生物医学成像与临床转化分论坛作报告，题为“用于无创实时监测伤口炎症的智能手机辅助双模式碳量子点敷料”。
3. 20260120-20260123，哈尔滨，担任2026全国传感技术与应用研讨会学术委员会委员并作报告，题为“基于碳量子点荧光探针的双模式可视化智能敷料用于伤口炎症快速监测”，获"科学探索奖"。
